Risk factors for klebsiella pneumoniae carbapenemase infection in intensive care units
DOI:
https://doi.org/10.35381/s.v.v9i2.4750Keywords:
Klebsiella pneumoniae, Risk factors, Intensive care units, Healthcare-associated infection, (Source: DeCS).Abstract
Objectives: To interpret risk factors for Klebsiella pneumoniae carbapenemase infection in intensive care units. Method: Systematic review following PRISMA 2020 methodology, including scientific articles such as systematic reviews, meta-analyses, case-control and cohort studies from 2018-2022 period in MEDLINE, COCHRANE, SCIENCE DIRECT and SCOPUS databases. Results: From 295 initial articles, 20 studies were selected. Main risk factors identified were: antibiotic exposure, thrombocytopenia, APACHE II score >15, prolonged ICU stay, use of invasive devices and burn unit hospitalization. Conclusions: Multiple modifiable risk factors exist for KNCP infection in ICU, whose early identification can contribute to developing effective preventive strategies and appropriate institutional policies for antibiotic use.
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