Uses of minocyclines through extended-release devices
DOI:
https://doi.org/10.35381/s.v.v6i2.2127Keywords:
Anesthesia, Dental, Biomedical and Dental Materials, Tooth Diseases. (Source, DeCS).Abstract
Objective: To know the uses of minocycline extended release devices focusing on the therapy of periodontal disease and the advantages of this treatment over conventional pharmacological therapy used in this pathology, as well as to determine the degree of knowledge of the teachers of the UAO (Dental Care Unit) UNIANDES about these devices. Method: Descriptive observational study. Results: 79% were not aware of the existence of minocycline delivery devices, while 21% were aware of the device. According to the results, 79% of people did not know about the minocycline extended release device. Conclusion: The extended release devices of minocycline microspheres achieve a higher bioavailability of the drug in concentration and action reducing the adverse effects and possibility of super infections of the drug.
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Breijyeh Z, Jubeh B, Karaman R. Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It. Molecules. 2020;25(6):1340. Published 2020 Mar 16. doi:10.3390/molecules25061340
Vila J, Moreno-Morales J, Ballesté-Delpierre C. Current landscape in the discovery of novel antibacterial agents. Clin Microbiol Infect. 2020;26(5):596-603. doi:10.1016/j.cmi.2019.09.015
Mühlberg E, Umstätter F, Kleist C, Domhan C, Mier W, Uhl P. Renaissance of vancomycin: approaches for breaking antibiotic resistance in multidrug-resistant bacteria. Can J Microbiol. 2020;66(1):11-16. doi:10.1139/cjm-2019-0309
Zhanel GG. Antibacterial drivers of resistance. Treat Respir Med. 2005;4 Suppl 1:13-18. doi:10.2165/00151829-200504001-00005
McManus MC. Mechanisms of bacterial resistance to antimicrobial agents. Am J Health Syst Pharm. 1997;54(12):1420-1446. doi:10.1093/ajhp/54.12.1420
Palacio PA, Herrera LM, Duque A. Sistemas de liberación controlada de antimicrobianos en periodoncia [Antimicrobial controlled release systems in oral health care]. Revisión de literatura. CES odontol. [Internet]. 2009; 21(2):69-77. Disponible en: https://revistas.ces.edu.co/index.php/odontologia/article/view/403
Fragkou PC, Poulakou G, Blizou A, et al. The Role of Minocycline in the Treatment of Nosocomial Infections Caused by Multidrug, Extensively Drug and Pandrug Resistant Acinetobacter baumannii: A Systematic Review of Clinical Evidence. Microorganisms. 2019;7(6):159. Published 2019 Jun 1. doi:10.3390/microorganisms7060159
Martínez Julio, Esmeralda Salazar de Plaza. Efecto de la Minociclina como coadyuvante en el tratamiento de la enfermedad periodontal [Effect of minocycline as an adjuvant in the treatment of periodontal disease]. Acta odontol. venez [Internet]. 2003; 41(1): 77-84.
Singh S, Khanna D, Kalra S. Minocycline and Doxycycline: More Than Antibiotics. Curr Mol Pharmacol. 2021;14(6):1046-1065. doi:10.2174/1874467214666210210122628
Fernández, Javier. Estudio in vitro de liberación de fármacos desde un biomaterial compuesto [In vitro study of drug release from a composite biomaterial]. Revista CENIC. Ciencias Químicas. 2016; 41(13): p. 1-8.
Jonas M, Cunha BA. Minocycline. Ther Drug Monit. 1982;4(2):137-145.
Garner SE, Eady A, Bennett C, Newton JN, Thomas K, Popescu CM. Minocycline for acne vulgaris: efficacy and safety. Cochrane Database Syst Rev. 2012;2012(8):CD002086. Published 2012 Aug 15. doi:10.1002/14651858.CD002086.pub2
Aronson AL. Pharmacotherapeutics of the newer tetracyclines. J Am Vet Med Assoc. 1980;176(10 Spec No):1061-1068.
Dannewitz B, Holtfreter B, Eickholz P. Parodontitis – Therapie einer Volkskrankheit [Periodontitis-therapy of a widespread disease]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021;64(8):931-940. doi:10.1007/s00103-021-03373-2
Teles FRF, Lynch MC, Patel M, Torresyap G, Martin L. Bacterial resistance to minocycline after adjunctive minocycline microspheres during periodontal maintenance: A randomized clinical trial. J Periodontol. 2021;92(9):1222-1231. doi:10.1002/JPER.17-0565
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